Glossary entry

English term or phrase:

low BRCA1 along with high ERCC1 and/or XPG

German translation:

niedrige BRCA1- und hohe ERCC1- und/oder XPG-Expression

Added to glossary by Veronika Neuhold
Oct 18, 2010 20:44
13 yrs ago
English term

low BRCA1 along with high ERCC1 and/or XPG

English to German Medical Genetics oncology, sarcomas, chemotherapy, trabectedin
A retrospective study indicates that a composite signature based on DNA repair profile, **including low BRCA1 along with high ERCC1 and/or XPG**, identifies a highly sensitive population with highly improved treatment outcome. This signature could be used for patient’s enrichment studies in sarcoma and on other malignancies sensitive to trabectedin.
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Ist hier eine "niedrige BRCA1- und hohe ERCC1-/XPG-Expression" gemeint?

"Eine retrospektive Studie weist darauf hin, dass mit einer ??? Signatur basierend auf einem DNA-Reparaturprofil **mit niedriger BRCA1- und hoher ERCC1-/XPG-Expression*** eine hoch sensitive Population identifiziert und dadurch das Therapieoutcome signifikant verbessert werden kann."

Vgl. http://haematologie-onkologie.universimed.com/artikel/dna-bl...

Proposed translations

+3
1 hr
Selected

niedrige BRCA1- und hohe ERCC1- u./o. XPG-Expression

Ja, ich würde hier auch "Expression" ergänzen.
Note from asker:
Danke!
Peer comment(s):

agree Dr. Anja Masselli
13 hrs
Danke Anja!
agree MMUlr
14 hrs
Danke Margret!
agree Harald Moelzer (medical-translator)
1 day 16 hrs
Danke Harald!
Something went wrong...
4 KudoZ points awarded for this answer.
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