Эффект цетиризина приписывали модели физиологического косвенного (или непрямого) ответа, в котором концентрация препарата в центральном компартменте связана с функцией ответа, описывающей ингибирование или стимуляцию затронутых факторов, входящего или результирующего сигналов регуляции ответа.

Контексты: That might be the system that controls the eyelid, for example. There is an input to the system--the approaching object--and an output from the system--the closing of the lid. The system simply responds to the input. (описываются системы регуляции, гомеостаз http://michaeldmann.net/mann2.html)
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As with any other control system, a response loop has three primary components: an input signal, integration of the signal, and an output signal. https://ay12-14.moodle.wisc.edu/prod/pluginfile.php/48621/mo...

Cellular receptors and sensory systems measure input signals. Responses flow through a series of downstream processes. Final output expresses physiological or behavioral phenotype in response to the initial inputs. ...The input signal arises from the extrinsic spatial and temporal fluctuations of chemical concentrations. The output follows from the chemical transformations of the reaction that alter concentrations. The overall input-output pattern of the system develops from the signal processing of the component subsystems and the aggregate architecture of the components that form the broader system. https://biologydirect.biomedcentral.com/articles/10.1186/174...

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