Glossary entry (derived from question below)
Czech term or phrase:
alfa a betalytické účinky
English translation:
effects on alpha and beta receptors
Added to glossary by
Dylan Edwards
Jan 6, 2017 20:01
7 yrs ago
Czech term
United Kingdom
Native in: English (Variant: British) 
Works in: Greek to English, Czech to English, Slovak to English, and 1 more.
alfa a betalytické účinky
Czech to English
Medical
Medical (general)
Amiodaron působí prostřednictvím účinku na draslíkové, sodíkové a kalcioví kanály, má však i *alfa a betalytické účinky*.
Perhaps 'alfalytikum' and 'betalytikum' are synonyms of 'alfa-blokátor' and 'beta-blokátor'?
Perhaps 'alfalytikum' and 'betalytikum' are synonyms of 'alfa-blokátor' and 'beta-blokátor'?
Proposed translations
(English)
| 4 +1 | effects on alpha and beta receptors |
Martin Janda
|
| 4 +1 | Amiodarone exerts an antiadrenergic effect by inhibiting alpha- and beta-rece |
Erzsébet Czopyk
|
Proposed translations
+1
20 mins
Martin Janda
Czech Republic
Czech Republic
Native in Czech
Specializes in field
Czech Republic
Related KudoZ points
:
158
Selected
effects on alpha and beta receptors
See the link.
4 KudoZ points awarded for this answer.
Comment: "Many thanks to all who responded."
+1
21 mins
Erzsébet Czopyk
Hungary
Hungary
Specializes in field
Hungary
sworn translator, linguist, DPO
Native in: Hungarian (Variant: Hungary)
Works in: Russian to Hungarian, Hungarian to Russian, Latvian to Russian, and 10 more.
Related KudoZ points
:
8
Amiodarone exerts an antiadrenergic effect by inhibiting alpha- and beta-rece
Cardiac Drugs | Atrium (Heart) | Heart - Scribd
https://www.scribd.com/doc/94514204/Cardaic-Drugs
Increases HR Prolongs QRS and QT intervals Potassium Calcium Abnormally wide, ... The oxygen depleted blood is returned to the heart via the vena cava ..... *Drugs: digoxin, amiodarone, beta blockers, calcium channel blockers, .... Most affect automaticity but and may also have an effect on contractility (may be wanted or ...
The effect of amiodarone pretreatment on survival of mice with ... - NCBI
https://www.ncbi.nlm.nih.gov/.../13181_2009_Article_B... -
Current drug therapy guidelines for resistant or hemodynamically stable ventricular tachycardia (VT) or ventricular fibrillation (VF) associated with cocaine are sodium bicarbonate followed by lidocaine. However, in the “Guidelines 2000 for Cardio-pulmonary Resuscitation and Emergency Cardiovascular Care”, amiodarone is the first line antidysrhythmic for VT and VF.
Amiodarone also blocks sodium channels ...
The purpose of this study was to evaluate the safety and efficacy of amiodarone pretreatment in a murine model of acute severe cocaine toxicity. We concluded that the sympatholytic and sodium channel effects of amiodarone would outweigh the potential detrimental effects of calcium and potassium channel blockade.
(Sympathetic stimulation of cardiac beta-receptors/beta sympathetic
blockade)
Amiodarone and beta blockade - Krause und Pachernegg
www.kup.at/kup/pdf/126.pdf
Amiodarone and beta-blockers are the two most widely used antiarrhythmic drugs. Although these agents share similar properties, they also have distinct pharmacological, pharmacokinetic and electrophysiological differences.
Pharmacology of Amiodarone
Amiodarone has a complex pharmacological profile and can inhibit sodium, potassium (Ikr and Iks) and calcium currents (IcaL). Amiodarone has a greater inhibitory effect on Ikr channels than on Iks channels. Its major antiarrhythmic properties are thought to be related to prolongation of the
action potential duration. Amiodarone also exerts an antiadrenergic effect by non competitively inhibiting alpha- and beta-receptors [14]. Unlike beta-blockers, amiodarone does not bind to the catecholamine recognition site of the betareceptor and appears to induce a significant decrease in the
number of beta-adrenoreceptors
--------------------------------------------------
Note added at 22 mins (2017-01-06 20:24:38 GMT)
--------------------------------------------------
Sorry until I made my search my distinguished colleague entered it faster...
https://www.scribd.com/doc/94514204/Cardaic-Drugs
Increases HR Prolongs QRS and QT intervals Potassium Calcium Abnormally wide, ... The oxygen depleted blood is returned to the heart via the vena cava ..... *Drugs: digoxin, amiodarone, beta blockers, calcium channel blockers, .... Most affect automaticity but and may also have an effect on contractility (may be wanted or ...
The effect of amiodarone pretreatment on survival of mice with ... - NCBI
https://www.ncbi.nlm.nih.gov/.../13181_2009_Article_B... -
Current drug therapy guidelines for resistant or hemodynamically stable ventricular tachycardia (VT) or ventricular fibrillation (VF) associated with cocaine are sodium bicarbonate followed by lidocaine. However, in the “Guidelines 2000 for Cardio-pulmonary Resuscitation and Emergency Cardiovascular Care”, amiodarone is the first line antidysrhythmic for VT and VF.
Amiodarone also blocks sodium channels ...
The purpose of this study was to evaluate the safety and efficacy of amiodarone pretreatment in a murine model of acute severe cocaine toxicity. We concluded that the sympatholytic and sodium channel effects of amiodarone would outweigh the potential detrimental effects of calcium and potassium channel blockade.
(Sympathetic stimulation of cardiac beta-receptors/beta sympathetic
blockade)
Amiodarone and beta blockade - Krause und Pachernegg
www.kup.at/kup/pdf/126.pdf
Amiodarone and beta-blockers are the two most widely used antiarrhythmic drugs. Although these agents share similar properties, they also have distinct pharmacological, pharmacokinetic and electrophysiological differences.
Pharmacology of Amiodarone
Amiodarone has a complex pharmacological profile and can inhibit sodium, potassium (Ikr and Iks) and calcium currents (IcaL). Amiodarone has a greater inhibitory effect on Ikr channels than on Iks channels. Its major antiarrhythmic properties are thought to be related to prolongation of the
action potential duration. Amiodarone also exerts an antiadrenergic effect by non competitively inhibiting alpha- and beta-receptors [14]. Unlike beta-blockers, amiodarone does not bind to the catecholamine recognition site of the betareceptor and appears to induce a significant decrease in the
number of beta-adrenoreceptors
--------------------------------------------------
Note added at 22 mins (2017-01-06 20:24:38 GMT)
--------------------------------------------------
Sorry until I made my search my distinguished colleague entered it faster...
Discussion
and an English definition for alphalytic: http://medical-dictionary.thefreedictionary.com/alphalytic
And, I would say yes, alfa/betalytikum is a synonym for alfa/betablokátor... betalytické účinky sounds familiar to me but I have never met betablokátorové účinky. Perhaps, that the reason why there is betalytické účinky when they speak about beta-blocking effect.