English to Russian Science Biology (-tech,-chem,micro-) физиология

Particularly in the case of dasatinib, the increased potency may be associated with untoward off-target toxicities, which probably relate to their inhibitory activity against a broader range of protein kinases such as Kit, PDGFR and ephrin receptor (EphA2) tyrosine kinases which are directly implicated in haematopoiesis, control of ***tissue interstitial-fluid pressure*** and angiogenesis.

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